We drive from UK to Corfu 2 or 3 times a year. This all depends on if you are carrying goods, are you in a hurry, do you want a cheap route or a fast route? We normally do the 'Northern route' to Venice which is much cheaper and misses those traffic jams in Italy. It involves about 16 hours drive time plus about 2 hours toilet and petrol stops. The Austrian Vignette costs 7.70 euro, the Brenner pass is 6 euro and you pay 6 euro for the Italian motorways. All routes seem to take about the same time. You can split this into however days you want The Venice ferry is more expensive and there are various prices depending if you want a cabin, a reclining chair or the camper deck. We just arrived 2 days ago after driving down. This time was the first time we had used Anek in this direction and although the ferry was OK we will use Minoan in future as it is just that little bit better. We looked at driving further down Italy but when you add an extra night stop plus petrol plus road tolls it's not worth it.
Dave, the white van man uses a very similar route I believe and he does the trip many times a year.
If you require any more info please let us know.